منابع مشابه
X-ray analysis of disodium cromoglycate.
Disodium cromoglycate (I; DSCG) was introduced in 1968 for the treatment of bronchial asthma. Evidence concerning its principal effects and possible mode of action has been described at some length in the recent literature (Cox, 1971 ; Cox & Altoanyan, 1970). Crystals of the compound exhibit a remarkable reversible water absorption (Cox, Woodard & McCrone, 1971), the number of water molecules p...
متن کاملDisodium cromoglycate in the treatment of chronic proctitis.
The effect of topical disodium cromoglycate (DSCG) has been examined in 30 patients with chronic active proctitis using a double-blind crossover trial. Each treatment period was four weeks and patients were given DSCG 200 mg by enema twice daily and 100 mg orally three times each day. Twenty-six patients completed the trial successfully, 14 responded to DSCG treatment, two improved with placebo...
متن کاملColumnar molecular aggregation in the aqueous solutions of disodium cromoglycate.
Stack, chimneylike, and threadlike assemblies have previously been proposed for the structure of disodium cromoglycate (DSCG) aggregates in aqueous solutions. The results of the synchrotron x-ray scattering investigations reported here reveal the formation of simple columnar assemblies with π-π stacking at a separation of 3.4 Å between the DSCG molecules. Lateral separation between the assembli...
متن کاملEffect of disodium cromoglycate (Intal) on sputum protein composition.
The protein content in the sputum of nine patients with asthma was compared with that in 11 non-asthmatic patients by a method of gel electrophoresis. It was found that the albumin content was significantly higher in the sputum of the asthmatics than of the non-asthmatics (P<001). A further 11 asthmatic patients who were taking disodium cromoglycate (Intal) as part of their treatment had sputum...
متن کاملEffect of disodium cromoglycate on exercise-induced asthma.
In eight patients with exercise-induced asthma, disodium cromoglycate was found to produce a definite inhibition of the post-exercise fall in forced expiratory volume in one second. This effect may be part of the cause for the subjective improvement experienced with this drug.
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ژورنال
عنوان ژورنال: BMJ
سال: 1969
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5657.634-b